Evaluation on Efficacy of Cefazolin Sodium Combined with Metronida-zole in Postoperative Incision Infection Patients with Uterine Fibroids

FENG Yun

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KANGGANRAN YAOXUE ›› 2019, Vol. 16 ›› Issue (7) : 1208-1210. DOI: 10.13493/j.issn.1672-7878.2019.07-035

Evaluation on Efficacy of Cefazolin Sodium Combined with Metronida-zole in Postoperative Incision Infection Patients with Uterine Fibroids

  • FENG Yun*
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Abstract

Objective: To evaluate the efficacy of cefazolin sodium combined with metronidazole in postoperative incision infection patients with uterine fibroids. Methods: 86 cases of laparoscopic myomectomy patients admitted from May 2016 to May 2019 were selected and divided into control group and observation group according to different treatment methods, with 43 cases in each group. Patients in the control group were treated with metronidazole alone 1 h before surgery, and patients in the observation group were treated with cefazolin sodium on the basis of the control group. The differences in the total effective rate, incidence of incision infection and incidence of adverse reactions were compared between the two groups. Results: The total effective rate (93.02%) of the observation group was significantly higher than that of the control group (72.09%) (P<0.05), and the incidence of incision infection (2.33%) was significantly lower than that of the control group (11.63%) (P<0.05). There was no statistically significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: The combined use of cefazolin sodium and metronidazole to prevent postoperative incision infection in patients with uterine fibroids after laparoscopic excision was more effective than using metronidazole alone, which effectively reduced the occurrence of incision infection and had a higher safety.

Key words

cefazolin sodium / metronidazole / incision infection / laparoscopic myomectomy / uterine fibroids

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FENG Yun. Evaluation on Efficacy of Cefazolin Sodium Combined with Metronida-zole in Postoperative Incision Infection Patients with Uterine Fibroids. KANGGANRAN YAOXUE. 2019, 16(7): 1208-1210 https://doi.org/10.13493/j.issn.1672-7878.2019.07-035

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