Objective: To analyze screening and drug resistance of multi-drug resistant bacteria in anal swab specimens of newborns in ICU of a hospital.Methods: 116 newborns admitted to ICU of Shangqiu Maternal and Child Health Hospital from March 2018 to November 2020 were selected as research subjects, and the species and drug resistance characteristics of multi-drug resistant bacteria isolated from the anal swab specimens of the children were analyzed. Results: 25 strains of multi-drug resistant bacteria were isolated from anal swab specimens of 116 newborns, mainly including 13 extended-spectrum beta-lactamase-producing Enterobacterales (ESBLs-E) (52.00%) and 10 vancomycin-resistant Enterococci (VRE) (40.00%). The drug resistance rates of ESBLs-E to imipenem, ampicillin-sulbactam sodium and cefoxitin were 0.00%; the drug resistance rates of VRE to linezolid and teicoplanin were 0.00%. Conclusion: The newborns in ICU of the hospital are seriously affected by multi-drug resistant bacteria, and the infected multi-drug resistant bacteria are mainly ESBLs-E and VRE. Clinically, the monitoring on multi-drug resistant bacteria should be enhanced, and antibacterial drugs should be reasonably selected according to the drug resistance characteristics of pathogenic bacteria to ensure the treatment effect.
Key words
newborn /
ICU /
multidrug-resistant organism /
vancomycin-resistant Enterococci /
extended-spectrum beta-lactamase-producing Enterobacterales
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